1/ 🚨It finally happened!!!🚨
— Dave Feldman (@DaveKeto) April 7, 2019
I now have an excellent academic partner who has a large dataset in hand (a well known one, btw). Now we are testing my many speculations over the last three years…
What of the triad (↗️LDL↗️HDL↘️TG) and ACM? of CVD? vs Standard guidelines?…
2/ Is it true that HDL can be safely ignored?
— Dave Feldman (@DaveKeto) April 7, 2019
How much impact do triglycerides have?
Does low LDL equal low CVD? And if so, does it come with low all cause mortality?
3/ All these questions and more will be explored over the coming weeks… I plan to do the big reveal of what we find at #KetoSaltLake.#RethinkLDL? Or will it be #EmbraceLDLLowering?
— Dave Feldman (@DaveKeto) April 7, 2019
Wow, that is fantastic news, Dave! Can’t wait to see what you make of it all.
Below I am posting my younger sister’s last cholesterol test results, from January. She’s Down’s and just on a “regular” diet. She’s due for another test this week, and then a doctor’s visit next week, but I thought I would go ahead and use the remnant cholesterol tool now just to see what it shows, then compare it to the new test results after her doc visit. This one shows her in the lower quintile for risk, and the atherogenic risk in the lowest third. Her doc has had her on a low dose statin (pravastatin 10mg/day) for several years now, and I am wondering more and more why, especially because of what I know now about the LDL number not being so important. I mean, look at her HDL and triglyceride numbers! She gets tested and sees the doc every 3 months (because of being on synthroid), and I’m thinking to ask the doc about skipping the statin till the next test in 3 months to see how her numbers do. Any thoughts on this? Thanks!
–==== CholesterolCode.com/Report v0.9.3 ====–
…50 years on Standard American ::: 12 hours water fasted…
Total Cholesterol: 189 mg/dL 4.89 mmol/L
LDL Cholesterol: 109 mg/dL 2.82 mmol/L
HDL Cholesterol: 68 mg/dL 1.76 mmol/L
Triglycerides: 61 mg/dL 0.69 mmol/L
–CHOLESTEROL REMNANTS–
Remnant Cholesterol: 12 mg/dL 0.31 mmol/L >>> Lowest Risk Quintile
Remnant Chol to HDL: 0.18 >>> Lowest Risk Quintile
Go to https://tinyurl.com/y84u92wm for more on Cholesterol Remnants
–ATHEROGENIC INDEX OF PLASMA (AIP)–
AIP: -0.407 >>> Lowest Risk Third
Go to https://tinyurl.com/ycccmmnx for more on Atherogenic Index of Plasma
–CONVENTIONAL MARKERS AND RATIOS–
Friedewald LDL-C: 109 | Iranian LDL-C: 91
Total/HDL Ratio: 2.78
TG/HDL Ratio in mg/dL: 0.9 | in mmol/L: 0.39
As usual, we don’t provide any medical advice, particularly with medication. The HDL and TG look very good, whatever diet she’s on. 🙂
Depends?
High hdl and low triglycerides might be one environment where higher ldl is associated with lower all cause mortality. Eric in Vegas
Would you be able to look into subset with very high HDL (let say over 100 mg/dL)?
Do they have higher risk of CVD or total mortality?
Hi, thank you Dave for your comment about my recent post of my sister’s last blood test. She just had another blood test, and we found out the results today during a visit to her doctor. I will post them below. The numbers are very similar to the last test. I asked her doctor about taking my sis off the statin (levothyroxine 25mcg/day), and he had the exact reaction I expected. Bad. And when I tried explaining my reasoning, from all the research I have done online, including watching many MDs, cardiologists, and cholesterol experts such as you and Ivor Cummins, the doc acted like I was crazy, telling me I shouldn’t believe stuff I see online, that there are so many “fringe” people trying to make names for themselves, etc. I told him LDL was the least important number after HDL and triglycerides, and he said no, it’s the most important number, and statins are needed to bring it down. Pretty much poo-pooed everything I had to say on the subject, but agreed it was up to me as one of my sister’s caregivers to decide what meds to give her. And yes I know you can’t give medical advice. Just wish I had remembered to ask the doc about ,remnant cholesterol and LDL particle size, to see if he even knew what those were and why they matter. Ok, here are her most recent results on a little better that standard diet (not low carb nor keto):
–==== CholesterolCode.com/Report v0.9.3 ====–
…6 years on Standard American ::: 12 hours water fasted…
Total Cholesterol: 182 mg/dL 4.71 mmol/L
LDL Cholesterol: 104 mg/dL 2.69 mmol/L
HDL Cholesterol: 67 mg/dL 1.73 mmol/L
Triglycerides: 57 mg/dL 0.64 mmol/L
–CHOLESTEROL REMNANTS–
Remnant Cholesterol: 11 mg/dL 0.28 mmol/L >>> Lowest Risk Quintile
Remnant Chol to HDL: 0.16 >>> Lowest Risk Quintile
Go to https://tinyurl.com/y84u92wm for more on Cholesterol Remnants
–ATHEROGENIC INDEX OF PLASMA (AIP)–
AIP: -0.432 >>> Lowest Risk Third
Go to https://tinyurl.com/ycccmmnx for more on Atherogenic Index of Plasma
–CONVENTIONAL MARKERS AND RATIOS–
Friedewald LDL-C: 104 | Iranian LDL-C: 84
Total/HDL Ratio: 2.72
TG/HDL Ratio in mg/dL: 0.85 | in mmol/L: 0.37
I am wondering if my triglycerides are elevated and have been keto a yr, now trying carnivore for a week now, and I am a coffee drinker of 1 cup in the morning.. Does that mean I need to stop coffee? I have fasting labs coming up on 4/30…just wondering. Also if they rise and I’m drinking coffee does that mean there is cause for concern?
Could you provide a little more information? What do your HDL, triglycerides, LDL, etc look like? Is the HDL normal? Triglycerides significantly over >130?
Do you match any of the other possibilities in this post, e.g. were you properly fasted for 12-14 hours before the blood test (water only)?
It’s hard to tell how likely coffee is as a culprit without more information. 🙂