Eating Window Experiment – Design and Prediction

Today I started the #EatingWindowExperiment, which is probably just what you thought it was by the title.

Experiment Design

There are two phases:

1. Eat baseline diet for five days in the usual 10 hour window (9am, 2pm, and 7pm eating times)
2. Eat the same baseline diet for five days, but compressed into a 4 hour window -> 4pm, 5:30pm, and 7pm 10am, 12pm, and 2pm eating times (*amended here)

Daily blood tests of glucose, ketones (BHB), and lipids (TC, LDL-C (calc), HDL-C, and triglycerides) will be performed at these times:

• Within 20m of waking up
• ~7 am
• ~9 am
• ~2 pm
• ~7 pm
• ~10 pm

Blood tests for mornings of January 13th and 18th

Labcorp:

• Apolipoprotein A-1
• Apolipoprotein B
• C-Reactive Protein
• Complete Blood Count (CBC)
• Comprehensive Metabolic Panel (CMP)
• Cortisol
• Fatty Acids, Free (NEFA)
• Ferritin, Serum
• Fructosamine
• GGT
• Glucagon, Plasma
• GlycA
• Hemoglobin A1c
• IGF-1
• Insulin and C-Peptide
• Leptin
• Lipid Panel
• Lipoprotein(a)
• Lp-PLA2 Activity
• Nuclear Magnetic Resonance (NMR)
• Oxidized Low-density Lipoprotein (OxLDL)
• Testosterone, Serum
• Thyroid Panel
• Uric Acid, Serum
• Vitamin B12 and Folate
• Vitamin D, 25-Hydroxy

Boston Heart Diagnostics:

• Adiponectin
• Cholesterol Balance
• Fatty Acid Balance
• HDL Map
• Interluekin-6
• Leptin (Redundant, but of high interest)
• Oxidized Phospholipids on apoB (OxPL)

Hypothesis

Honestly, I don’t have a lot to add with regard to the hypothesis. This is more of an exploratory experiment.

If I had to pick one thing I’d predict, I’d lean toward there being a higher fasting glucose and insulin level resulting from the bigger meal of the tighter eating window from the night before. However, that doesn’t mean that these two would be higher in the “area under the curve”. But fortunately, we’d have some data to speculate on that given my high frequency testing throughout the day.

Again – this is more of a “let’s see what happens” experiment.