Eating Window Experiment – Design and Prediction

Today I started the #EatingWindowExperiment, which is probably just what you thought it was by the title.

Experiment Design

There are two phases:

  1. Eat baseline diet for five days in the usual 10 hour window (9am, 2pm, and 7pm eating times)
  2. Eat the same baseline diet for five days, but compressed into a 4 hour window -> 4pm, 5:30pm, and 7pm 10am, 12pm, and 2pm eating times (*amended here)

Daily blood tests of glucose, ketones (BHB), and lipids (TC, LDL-C (calc), HDL-C, and triglycerides) will be performed at these times:

  • Within 20m of waking up
  • ~7 am
  • ~9 am
  • ~2 pm
  • ~7 pm
  • ~10 pm

Blood tests for mornings of January 13th and 18th


  • Apolipoprotein A-1
  • Apolipoprotein B
  • C-Reactive Protein
  • Complete Blood Count (CBC)
  • Comprehensive Metabolic Panel (CMP)
  • Cortisol
  • Fatty Acids, Free (NEFA)
  • Ferritin, Serum
  • Fructosamine
  • GGT
  • Glucagon, Plasma
  • GlycA
  • Hemoglobin A1c
  • IGF-1
  • Insulin and C-Peptide
  • Leptin
  • Lipid Panel
  • Lipoprotein(a)
  • Lp-PLA2 Activity
  • Nuclear Magnetic Resonance (NMR)
  • Oxidized Low-density Lipoprotein (OxLDL)
  • Testosterone, Serum
  • Thyroid Panel
  • Uric Acid, Serum
  • Vitamin B12 and Folate
  • Vitamin D, 25-Hydroxy

Boston Heart Diagnostics:

  • Adiponectin
  • Cholesterol Balance
  • Fatty Acid Balance
  • HDL Map
  • Interluekin-6
  • Leptin (Redundant, but of high interest)
  • Oxidized Phospholipids on apoB (OxPL)


Honestly, I don’t have a lot to add with regard to the hypothesis. This is more of an exploratory experiment.

If I had to pick one thing I’d predict, I’d lean toward there being a higher fasting glucose and insulin level resulting from the bigger meal of the tighter eating window from the night before. However, that doesn’t mean that these two would be higher in the “area under the curve”. But fortunately, we’d have some data to speculate on that given my high frequency testing throughout the day.

Again – this is more of a “let’s see what happens” experiment.

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3 years ago

Where you can order the Boston Heart tests without a doctor?

3 years ago

I have settled on 2 meals/day: 7AM and 12 PM then 19 hr fast and test blood sugar/ketones when I get up between 4:30-5:00 AM then right before I break fast at 7 AM. Glucose is usually about 100; ketones 1.1 between 4:30 and 5 then glucose drops to around 85 by 7AM; ketones stay the same. I will be very interested in your results. I am hardly ever very hungry by lunch at 12PM but eat because I am after the fasting benefits. I will be so interested in how an additional meal in the compressed window works for you! Good luck and keep us posted.

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