Discussing the LMHR Study on the Diet Doctor Podcast

I had a great chat with Dr. Bret Scher, Medical Director of Diet Doctor, on the newly launched Lean Mass Hyper-responder study.

0:00 Introduction

3:06 Welcome, Dave Feldman

4:06 A rise in cholesterol for people on keto

12:05 Dave’s pushback in his research

20:14 Thoughts on the recent Women’s Health Study paper

29:39 Exciting news about Dave’s upcoming research

37:10 The concern about the data from a one-year study

43:26 What Dave hopes to achieve with the study

47:48 Switching saturated to mono-unsaturated fat in lowering LDL?

53:33 About Dave’s other work: Own Your Labs

1:03:49 Blood glucose and insulin on hypo and hyper caloric intake of low carb

1:08:40 Where to find Dave Feldman

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3 months ago

Great interview., I would love to participate in your study such a pity don’t live in US. I’m 65 LDL =260 . HDL =80, Trig =55. HbA1c = 5.1. My CAC score was 43. Will test again next year. Can’t wait to see the results of this study. Huge Congratulations Dave!!

Dan Wagner
Dan Wagner
2 months ago

Dave, I fit the LMHR phenotype. How can I contact you about participating in your study? I’m in the US. Last 2 lipid panels LDL was 550, HDL over 80, triglycerides 53 and 74, respectively. Thanks and best regards!

Siobhan Huggins
Siobhan Huggins(@siobhanh)
1 month ago
Reply to  Dan Wagner

Hi Dan, you would need to contact the Lundquist institute, not Dave, to see if you qualify and how to proceed if so. Info on contact for the institute is here.

Jennifer Wade
Jennifer Wade
1 month ago


Jennifer Wade
Jennifer Wade
1 month ago

Hello, iv been binge listening to your podcasts today. I would love to be in you study but I’m afraid to fly. Iv always had problem with cholesterol. But recently I had went for other blood work and they also took my cmp.. I had been fasting for three n half days. Having coffee with cream. My numbers were highest they have ever been. I know you had same experience as mentioned in a podcast. My A1c 11.8, my total Chol 580, LdL500,HdL41, Trig197. I am a mess. I do have atherosclerosis. I have tried to stick to carnivore but recently fell off after loss of mom. I was back to eating the sad diet. To say I need help is an understatement. I have given in to my Dr n started taking stations. I refuse to take metformin. But I am back to the carnivore woe. So I know my sugars are going down. Any advice šŸ™

Siobhan Huggins
Siobhan Huggins(@siobhanh)
1 month ago
Reply to  Jennifer Wade

Hi Jennifer,
First off, I’m so sorry to hear of your loss. That must be very difficult, and I think struggling with diet – regardless of what it is – under such circumstances is understandable. My thoughts are with you and your family.
We’re not doctors and can’t give medical advice, so can only comment with our opinion in case it may be of interest.
With regards to testing lipids while fasting for an extended period (e.g. 24+ hours) both Dave and I have found that this can skew lipid results (e.g. result in lower HDL, higher LDL, and higher triglycerides to name a few). Alongside this, we’ve likewise seen in ourselves and others that not properly fasting (e.g. water only fasting with no coffee, tea, or caffeine during that fasting period) may also confound results.
Although, as mentioned, we can’t give medical advice if it were me and I were in a similar situation I’d likely want to re-test 12-14 hours fasted water-only (no coffee, no tea, no caffeine as mentioned) while maintaining a steady diet (without extended fasting) for five days or so prior to the blood draw just to clarify under more stable conditions.

Would love your thoughts, please comment.x