I mean for this post to serve as a transparent and prospective article of scientific intent, not a contract or final document. I will express the aim, describe the design, pose my hypothesis and provide considerations. Overview: Aim: To assess the impact of Oreo supplementation versus statin therapy on LDL-C levels in a lean-mass hyper-responder …
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May 20
One Year Since Publication of the Lipid Energy Model
On this day last year, May 20th, 2022, we published the Lipid Energy Model in Metabolites. To say this was a milestone in my unlikely journey into research would be an understatement. The Lipid Energy Model (LEM) started as a simple idea around why I suspected my LDL cholesterol (LDL-C) would rise substantially on a …
Feb 09
LMHR Study Recruitment Complete
We’re beyond excited to announce the Lean Mass Hyper-Responder has completed enrollment. Needless to say, this has been a long awaited milestone. We’ve updated the recruitment page at CSF to let everyone know we are no longer taking participants for the study. Again, each of our 100 participants will make a total of two trips …
Jan 27
The New Cholesterol Code – Less Comments, More Research
Hello everyone! You may have noticed we’ve been posting less frequently here at CholesterolCode.com (CC). This isn’t for lack of interesting things to share and update you on – it’s because Siobhan and I are now fully entrenched in both formal research through the CitizenScienceFoundation.org and expanding our blood testing service, OwnYourLabs.com. A Quick Recap Here’s …
May 28
Lean Mass Hyper-Responder: Is it the saturated fat?
It’s a question that comes up again and again: Could Lean Mass Hyper-Responders (LMHRs) just be eating more saturated fat? Rather than repeatedly answering this question in cumbersome Twitter threads, I thought I’d save both Dave and myself some time by consolidating 5 points that challenge the saturated fat hypothesis of LMHR: 1. Magnitude of effect. Many …
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