Jul 23

Ketofest Cholesterol Presentation Blowout

Yesterday was an amazing experience!

It was the second Ketofest held by the 2 Ketodudes in New London, CT. And as with the first year, the last day was reserved for “Science Sunday”. On deck were many speakers including yours truly. But never mind my presentation, I want to tell you about three others that cumulatively made my year…

The Paradox of Insulin Resistance versus LDL Cholesterol – Dr. Nadir Ali

Nadir had an extremely fascinating discussion on LDL cholesterol, insulin resistance, longevity, and even the problems with how industry conducts the science on how we study heart disease.

He had a number of graphs, flow charts, and illustrations that brought through the message impressively. He even covered lesser known protective aspects of LDL such as disrupting quorum sensing used by bacteria.

Your Marvelous Mevalonate Machine vs the Statin Slayer – Nick Mailer

I don’t even know where to begin with this spectacular presentation. Nick took us on an animated journey though biochemistry like nothing I’d ever experienced before. He painstakingly animated nearly every slide so we could observe the processes he was describing in deep detail as though it were happening in front of our eyes.

While it was delightful to see his naming me as one of his inspirations for taking his presentation in this direction, I can assure you he certainly took this to the next level. If you like my use of animations for presentations, imagine this increase by an order of magnitude… and for the record, I’m being quite literal here!

LDL: Primed to Protect (Cholesterol’s role in defense and repair) – Siobhan Huggins

I saved Siobhan’s speech for last as I can’t even begin to describe impressive it was. She has been working tirelessly on it for quite a while, and the effort truly shows. She managed to strike the perfect balance between dense content and friendly, accessible illustration.

She discussed her personal journey into the research, the many roles of LDL, Lp(a), and the lipid system as a whole. Moreover, she elucidated the common misconception of inflammation and how it should be understood for the process of repair rather than the problem it’s addressing in the first place. And perhaps most important of all, she wraps it up with a discussion on the importance of not taking any marker in isolation and to see the system as a whole.

It’s worth pointing out this was Siobhan’s first presentation in front of a live audience and as many of us agreed, she knocked it out of the park. 😀

A Truly Good Day

As I remarked several times yesterday, I felt genuinely ecstatic for how powerful the messages came across from everyone above on the subject of lipids and cholesterol in particular. I’m not sure when all these videos will be available on YouTube, but we’ll certainly have a post up when they are — and I’d certainly give each of them my highest recommendation.

Jul 18

The Trifecta Tour

For the next couple weeks I’ll be taking a lot of planes, trains, and automobiles…

The Tour begins

Yes, while the Mrs holds down the fort at home, I’ll be bouncing around the U.S. doing three presentations in 8 days:

  1. Ancestral Health Symposium in Bozeman, MT, where I will speak on the 19th
  2. Ketofest in New London, CT, where I’ll speak on the 22nd
  3. Low Carb USA in San Diego, CA, where I speak on the 27th

Although those arrows make it look easy, I’ll actually have to navigate a bunch of connecting flights, train and road trips throughout as both Bozeman and New London aren’t near a major airport of any kind. Meh!

But wait… there’s more…

While in San Diego:

Needless to say, it’s going to be a pretty intense couple of weeks.

Siobhan’s Speaking Debut

Also at Ketofest, Siobhan Huggins will be giving her first full presentation, “LDL: Primed to Protect (Cholesterol’s role in defense and repair) ” this coming Sunday at Ketofest. Spoiler alert — I’ve gotten a sneak preview and it’s going to be fantastic!

So Heads Up, Internet – We’re Busy!

With all this in mind, don’t be surprised if both my and Siobhan’s activity here at Cholesterol Code and on social media in general is drawn down for the week.

Jul 09

I’m Booked to Appear on Peter Attia’s New Podcast

No, that’s not a misprint. I’ll be joining Attia in a couple weeks at his offices in San Diego to record an episode that I’m sure will have a lot of people talking.

This has actually been determined for a while, but I was planning to keep it on the down low until closer to the appearance. Naturally, the podcast with Peter and Ron Krauss got a lot of people both requesting I respond and pressing for Peter to have me on the podcast.

So for the record, when I sent out this tweet:

Note the booking and this tweet were up before the Krauss interview got posted. No need to ping Peter anymore — he was ahead of you all along!

Without question, I’m extremely excited to chat with him about the Lipid Energy Model and it’s relevance to lipoprotein and cholesterol homeostasis. I’m confident it will be unlike any podcast I’ve been on before and I’ll apologize in advance for what may be a lipid geekfest.


Jul 04

High Triglycerides on Low Carb – And What to Do About It

Triglycerides (TGs) are effectively fat-based energy. And if you’re on a low carb, high fat diet (LCHF), you are likely eating them every day, along with storing them as such in your own fat cells. The “tri” is for the three fatty acids grouped in each one to a glycerol backbone.

So a common question I get is, “Hey, if we’re powered by triglycerides on LCHF/Keto — then why do my blood tests show my triglycerides have gone down since I started?”

Simple… your usage has gone up. Way up! And that’s a good thing!

Generally speaking, you want to aim for having your triglycerides below 150 mg/dL at a minimum, and preferably below 100 mg/dL for optimum health. I consider this universal, by the way. It doesn’t matter if you’re on a LCHF/Keto, Vegan, Paleo, Mediterranean, or Bob’s Special Custom Juice and Burger Diet. If you have high triglycerides, it suggests a problem — and certainly a problem I pay attention to more than any other marker.

Steps to Take

Here is my general checklist:

  1. Confirm you water-only fasted for 12-14 hours before your cholesterol test. (No food, no coffee, just water) The more outside that window you are, the more it can increase your TGs (especially if near a fatty meal).
  2. You have a coffee sensitivity. I know, I know, I hate to be the bearer of bad news. But we’ve found a surprisingly large number of low carbers who see their triglycerides stubbornly high from what appears to be coffee alone. Note this is just a fraction of the coffee drinkers as most of them appear to be doing fine.
  3. You may have “carb leaks”. Get serious about tracking your food. Be really, truly, absolutely sure you’ve accounted for all carbs in the diet. Common unaccounted-for leaks include sauces, spices, beverages, alcohol, and many things labeled “0g Carb” that actually aren’t (rounded down in some nutrition labels) such as some brands of Heavy Whipping Cream. Sometimes you want to use a glucometer to detect what is actually higher carb than you thought. Bottom line: many who have even moderate carbs while on a LCHF diet can see their TGs spike because it’s still too much of an energy surplus.
  4. Cut out refined/liquid/concentrated forms of fat. Drop bulletproof coffee, oils, fat shakes, fat bombs, etc. Move toward as much fat from real food sources as possible.

These above steps I’ve worked with family and friends on when TG is high and it’s had a very high success rate, save two people.

Jun 29


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