Sep 11

Ketofest 2017 Presentation

This has turned out to be one of my favorites thus far. Just two quick notes:

  • I was karate chopping throughout as a way to visually have them advance slides as the clicker wasn’t working well that day.
  • If you’re already familiar with the boilerplate beginning that I usually have, you can skip ahead to where I present some of the newer data I haven’t covered as much in other presentations.

Of course, the preliminary results of the Ketofest Cholesterol Experiment are now posted.


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  1. bill

    Good good good!

    1. Dave

      Thanks, thanks, thanks. 🙂

  2. James Bond

    You’re drawing too much blood which may skew some of the results, and give you anemia in the long run 😛

    1. Dave

      I check my iron regularly and actually have a high Ferritin count, which is why I’ve been experimenting with giving blood at the blood bank. (As though I don’t give enough blood to science!)

  3. Loz

    Excellent video, Dave! I recently had my cholesterol panel done and nearly passed out when I got my results. My total C was 444, LDL was 332, HDL 98, trigs 38. My doc wants to send me to a cardiologist but I want to hold off. I’m going back in about 4 weeks for another draw. The thought is to drastically reduce saturated fats, with a strong focus on MUFAs and I think I’m going to use your protocol prior to testing. I used nearly all saturated fats prior so I’ll see what this round provides. What other details do you need to feed back this information for your studies?

    1. Dave

      Hi Loz,

      Of course, your profile immediately struck me as a Lean Mass Hyper-responder ( cholesterolcode.com/are-you-a-lean-mass-hyper-responder/ ).

      Are you lean and/or athletic? (In your case, I’d bet *both*) Are you likewise very good at staying strict about keeping your carbs down since starting this diet? (Not much cheating or drop offs…?)

      1. Loz

        Hi Dave,
        I’m athletic and I’d say on the lean side (no more than 10 pounds to lose max). I’m incredibly strict about my carb intake since being keto for the past 7 months. I’ve only recently gone up to 15 total carbs daily…and no cheats at all. I really want to make keto a lifestyle-I found so many benefits…and I’ve done everything in the past few days to acquire as much information as possible on being a hyper responder. Any thoughts on limiting the saturated fats or do you think that’s not necessary? I’ve also wondered if free range vs traditional farmed animals matter…I’ve read animals that are free range and grass fed have higher ratios of Omega 3 to 6 so that would certainly help with inflammation levels-though my CRP was 0.5, and I’m not terribly picky about meat source.

        1. Dave

          Ah yes — so your numbers make *perfect* sense.

          You’re keeping your carbs super low, thus necessitating more LDL trafficking to deliver TG to cells, especially when lean and athletic. If your LDLc/p is concerning, you might consider bringing up your carbs in replacing fats. While it varies from one person to the next, I find it will be likely given the mechanisms involved and have demonstrated this in my recent experiments ( see cholesterolcode.com/cholesterol-research-breakthrough/ and http://cholesterolcode.com/energy-status-experiment/ )

          Some have reported that reducing saturated fats succeeded in reducing LDL, but I’m skeptical on how significant it would be a for a low carber given — again — the mechanisms involved. The nature of the fat likely wouldn’t change the need of your cells for having it in the first place.

          Yeah, your CRP of 0.5 is likewise suggestive you’re in a state of very low inflammation.

          This is a very personal decision and I’d certainly what you to make it as informed as possible. Obviously, I personally take no steps to lower my cholesterol at this time even though I’m hyper-responder as well (and on the cusp of LMHR). But that’s because all of this makes mechanistic sense to me given what I’ve both learned and demonstrated through my experiments. (I always qualify “at this time” because I go where the data does.)

  4. Loz

    Gotcha. It would be worthwhile then to get the additional testing to discern the LDL in terms of particle size and count. I’d prefer not to incorporate any additional carbs if it’s not absolutely dire. Given that it only takes 3 days to make changes to your panel, I suppose it would be fine then to continue eating as I had been until prior to my next blood draw. I believe that would also yield the most accurate and current information as to how my body is processing the foods I’m choosing to eat.
    The work you’ve done is fascinating and I definitely think new base line “norms” should be re evaluated for those of us on LCHF. I’ll be sure to report back for your research purposes!

  5. Saleem

    Loz . i almost had a heart attack going through your numbers. good luck and please keep us posted with your new results. would it be too much to ask you to notify me once you post your results.


    1. Loz

      Not a problem Saleem. As someone who works in the medical industry, I’m sure you can imagine how I must have felt! What I will note is that the more I educate myself on the topic, the more I feel calm about it. Being a hyper responder is certainly not a comforting thing…but I am beginning to come to the conclusion that it’s not a dangerous thing.

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