Category Archive: Beyond the Lipid Hypothesis Series

May 18

Beyond the Lipid Hypothesis (Part 3): What’s Insulin Got to Do With It?

It Began With a Question… In the two previous parts of this series I covered what I had learned about how foam cell and plaque formation occur, and the process and circumstances of LDL modification. Throughout learning and writing about those topics I kept thinking about Ivor Cummins’ presentation, in which he discussed insulin’s role …

Continue reading »

Nov 01

Beyond the Lipid Hypothesis (Part 2): LDL Modification

Recap and Lingering Questions In part one of Beyond the Lipid Hypothesis, I covered the general process of plaque development, from the appearance of endogenous and exogenous pathogens, all the way up to plaque rupture and artery blockage. I studied this to truly examine the mechanisms and development of these fatty streaks and lesions that …

Continue reading »

Aug 24

Beyond the Lipid Hypothesis: Plaque Development

Note from Dave– Rarely have I been so impressed with the aptitude and intelligence of a researcher as I have with Siobhan. Her tenacity and resolve to absorb this subject is nothing short of jaw-dropping and I’m incredibly excited to have her fill in our deep dive on this crucial subject. Enjoy!   In the Beginning… …

Continue reading »