«

»

Jan 19

A Simple Guide to Cholesterol on Low Carb – Part II

In A Simple Guide to Cholesterol on Low Carb Part I, I gave a very broad overview of LDL particles and their important cargo along with common misconceptions about this subject within a low carb, high fat diet.

Without question, the guide was the most visited post on my blog. And many of my followers have remarked on how helpful the graphics were in getting across the information. So I decided to get ambitious with Parts II and III and tell it more as a visual story. In short – more graphics, less blog text. Enjoy!

cover

Page_01

Page_02

Page_03

Page_04

Page_05

Page_06

simple_guide_7b

Page_08

Page_09

Page_10

Page_11

Page_12

simple_guide_13a

155
Leave a Reply

avatar
 
Photo and Image Files
 
 
 
Audio and Video Files
 
 
 
Other File Types
 
 
 
49 Comment threads
73 Thread replies
4 Followers
 
Most reacted comment
Hottest comment thread
49 Comment authors
DaveThom ManningLizRobbieBryan Recent comment authors

  Subscribe  
newest oldest most voted
Notify of
Luke
Guest

Simple and to the point. Look forward to the part 3.

Hyper-Responder Neville
Guest
Hyper-Responder Neville

Using cartoons to explain lipid metabolism is so cool! really great work.
In case anyone’s interested (apart from the above series ^), this is probably one of the best explanations of this topic [https://www.youtube.com/watch?v=998r-MyEEPc] that i have come across.

Wim Tilburgs
Guest

Great article shared it in the Dutch Low Carb community.

Nicole recine
Guest
Nicole recine

Thanks so much for this Dave. Am I right in understanding that the LDLs become small and dense when they are lacking in cholesterol and have a lot more trigs to drop off?

michael pollard
Guest
michael pollard

Can’t see any way to subscribe.

Dr Z
Guest
Dr Z

Excellent site and excellent illustration!!

Any info on Wellbutrin use and elevated cholesterol? Long and complicated history, but would love any leads if you have come across any associations in your research. Thanks again and keep it up! This information needs to get out!

Megan

Joe
Guest
Joe

Hello Dave….

We chatted quickly on Twitter the other night, we had similar numbers and weight loss on LCHF. Here are my numbers again, before LCHF and one year later on LCHF. You said that you are taking no steps to lower your cholesterol at this point but told me to comment here for further explanation…Very interested!

Thanks….Joe

Jan 2016 Jan 2017

Weight 206 173

Cholesterol 223 373

HDL Cholesterol 65 92

Triglycerides 101 79

LDL / Cholesterol 138 265

Chol / HDLC Ratio 3.4 4.1

Non HDL Cholesterol 158 281

Gale
Guest

Hey Dave,

Just wanted to say what a great job you did presenting at the Low Carb Conference.

Keep up the great work.

Gale Bernhardt

Eric
Guest
Eric

Dave

Love your work also loving LCHF. Got Lab work back after being LCHF for several months. Stopped 10mg Lipitor after taking for 15 -20 years six months ago.

HDL-C 71 was 46 on HCLF +10mg Lipitor
LDL-C 170 was 95 on HCLF + 10mg Lipitor
Triglycerides 65 was120 on HCLF + 10mg Lipitor
HDL-P total 34.5unmol/L first time measured
Small LDL-P 625umol/L first time measured
Large LDL-P 1552umol/L first time measured
Total -C 254 was 161 on HCLF + 10mg Lipitor

Only number that I don’t like is the Small LDL-P which is just slightly out of range it’s 625 and reference high is 527. I know your not a MD but what’s your take?

Thanks

Eric

Eric
Guest
Eric

Do you have any concern over Large LDL-p?

Lita Santos
Guest
Lita Santos

OMG I’m so glad I found you. Just heard your Breckenidge talk. I’m Jill. I’m her. 7 months on keto and took the cholesterol test and almost fell off my chair. I couldn’t believe it had shot up so much. total cholesterol went up, LDL went up, HDL went up but not by much. My ratios were worse I couldn’t see a way to explain it favourably. I wrote to Dr Ken Sokardis, Gary Taubes, Jimmy Moore, Dom De’Agostino, Stephen Phinney, Malcolm Kendrick and a few others. Most wrote back some with good news others not so much. How can I email you please? I’ve encouraged my mother and sister onto this diet – I’ve even started a degree in Nutritional science and now I am feeling so deflated. Scared to eat fat. Scared not to and put on all the weight I lost. I don’t know what to do.

Brian Williams
Guest
Brian Williams

Hello Jill,

I have exactly the same situation. The important things are the two ratios: TotCl/HDL and TG /HDL

As long as they are ok, I don’t worry about cholesterol. You can improve HDL with fish oil EPA & DHA.

I use this for my guidelines: “Cholesterol Conundrum – Know Your Metrics” on Youtube https://www.youtube.com/watch?v=YRFRRqe0vrE

Good luck,

Brian

Pat
Guest

Do you follow Dr. Peter Attia at all? He has had quite a change of position on Ldl(a)-P in the last few years mainly I think through lots of feedback from Dr Tom Dayspring. Large particle number=arterial damage. Any comments?

Pat
Guest

Hi Dave–Do you follow Dr. Peter Attia’s Eating Academy blog? Nice detail and for sure he has an increasingly negative standpoint re Lp(a)-P. I think from more in-depth conversations with Dr Tom Dayspring. It is indeed a hot area of research but Dr Attia seems to be settiing the tone of high-P=artertial damage (no matter the particle (i.e. any Cholesterol). Any thoughts?

Ben
Guest
Ben

Very cool illustration. One detail seems to need attention, though. Perhaps I’ve missed something somewhere, but from what I understand, small LDL particles and vLDL are not the same thing. I used to think they were, until I was called out on it, and did more some research on it.

Further research showed me that there are actually five major groups of lipoproteins: (1) chylomicrons, (2) vLDL, (3) LDL, (4) IDL (intermediate density lipoprotein) and (5) HDL.

LDL particles vary in size and density, as we know. Larger, less-dense particles are referred to as Pattern A LDL, whereas smaller, dense particles are referred to as Pattern B LDL (or “LDL-P small”).

vLDL is a completely different lipoprotein than LDL, and tends to have a direct relationship with trigylcerides. Higher triglycerides = higher vLDL, and smaller triglycerides = lower vLDL. However, I’ve seen cases in which small LDL particles can be high, even when trigylcerides are low.

I’d be interested to know your thoughts on this. Thanks!

Ben
Guest
Ben

Thanks for the clarification. It just seems easy to misunderstand from your sixth slide, which states that there are two types of LDL, and it seems to say that one form of LDL is vLDL. The 7th slide seems to state that the other form of LDL is the chylomixron. Glad to hear that this is not truly what you were trying to communicate.

Brian Williams
Guest
Brian Williams

Hello, this is a great series! Any idea when Part 3 will be out?

Thanks!

Rafael
Guest
Rafael

So basically I don’t have to worry about having a 321 mg/dl cholesterol and a 240mg/dl LDL right now?

greylearning.com
Guest

Foods like oatmeal, apples, prunes, and beans are high in soluble fiber, which keeps your body from absorbing cholesterol.

rebt.com
Guest

Foods like oatmeal, apples, prunes, and beans are high in soluble fiber, which keeps your body from absorbing cholesterol.

stan straub
Guest
stan straub

I have been on LCHF for about a year. I have lost weight, feel good. I had a cholesterol PARTICLE test done. My doctor who ordered it then called, and said “we need to do something about your cholesterol”. Before I started LCHF, my cholesterol levels were moderate, NOT high (according to the standard cholesterol test and my doctors opinion). Now they are high. But I’m not able to interpret the results, and I’m a little fearful. My doctor won’t help me interpret the results…..he just sees “high”. If I give you the results, can you help me with deciphering them? I sent them to Dr. Andreas Eenfeldt at Dietdoctor.com and he said “As far as I can see these numbers are relatively average for the population. Hard to give a more useful reply without knowing your other health situation and what the numbers looked like before LCHF, etc.”. Not too helpful.
These are my results. I would sure like some peace of mind, one way or the other, if you would be so kind as to help me.

LDL-P = 1836
LDL-C = 208
HDL = 47
Tryglicerides = 65
Cholesterol = 268
HDL-P = 26.1
Small LDL-P = 371
LDL Size = 21.7
LP-IR Score = 33

Thank you so much.

Craig
Admin

This is the rabbit hole many of us have fallen into, finding out that establishment nutrition/health practitioners have serious flaws in their understanding of cholesterol, but not sure what to do about it.

If your concern is CVD, from my understanding of the research, the best test is to get a calcium score from a CAC. LDL is only very weakly predictive and possibly only so because its a marker for insulin resistance.

For me, my wife is in the category of concerned and not (yet?) well-read. Getting the CAC test (assuming my result is good) will be sufficient for her to let me KCKO. As far as my doc, I’m not sure if I want to switch, educate, or ignore. I’m gathering some data using the Feldman protocol so that my next appointment will be more interesting.

Michael Lawson
Guest
Michael Lawson

Your numbers are very similar to mine. I too have been LCHF for about a year and half now and feel great because of it. My reason was not so much weight loss ,but to get relief from post concussion syndrome, which it helped greatly.

I was concerned about the LDL-P being high after reading Dayspring/Attia thoughts on this, but Jimmy Moore says high LDL-P isn’t necessarily a problem as he has carried an absurdly high LDL-P (over 3000) with a CAC of 0 and CIMT scan showing no arterial blockage.

This doc also shares the same sentiment on LDL-P:
http://azsunfm.blogspot.com/2012/09/font-definitions-font-face-font-family.html

My numbers:
comment image

Craig
Admin

Thanks for sharing that your numbers and that link, it was a great read. Certainly relevant for my situation.

Pieta
Guest

Hi,
I am a medical doctor from South Africa. Hyper-responder on LCHF. Cholesterol now at 9mmol/l (360)
would like to partake in your study.

Pieta

Vaduvur Kumar
Guest

Part 1 & 2 are really informative.

carmelchamba.org
Guest

Foods like oatmeal, apples, prunes, and beans are high in soluble fiber, which keeps your body from absorbing cholesterol.

kk lim
Guest
kk lim

Hi Dave,
My mum have been on LCHF for close to 10 months now and a comparison of her lipid panels shown below (before and after LCHF):

(in mg/dL)
Total Cholesterol : 313 to 444
Triglyceride : 242 to 102
HDL : 50 to 60
LDL : 214 to 364
TG/HDL : 4.84 to 1.7

1. Is she what you would consider a “hyper-responder”?
2. Obviously the worry here is the upshoot in her LDL. But I told her that all her other important markers have improved – increased HDL, reduced Triglyceride, improved TG/HDL ratio. Her BP is normal and she has reduced her BP medication by half (50% less frequent intake of BP pills).
Are her worry confounded? Or am I too optimistic?
3. She also conducted a lipid sub-fraction test and she has about 27% small LDL (percentage excludes VLDL). Her VLDL number is 51 mg/dL. I.e. she has overall Pattern B particle size. Is that something to worry about?

Thanks.
kk

Chuck W
Guest
Chuck W

Dave,

Enjoying your blog, videos, and cartoons!

I had a couple questions regarding lipoproteins:

Are VLDLs/LDLs _delivering_ cargo to fat tissue, _picking up_ cargo from fat tissue, or a little bit of both?

During conditions of fasting and/or low carb dieting, what is the primary energy transport from fat tissue to other tissues of the body? LDLs? HDLs? Free fatty acids?

Thanks!
-Chuck W

Craig
Admin

Chuck,

Glad you found us! Fat is continually cycling through the body.

To adipose (fat tissue):
1. VLDLs deliver TG from the liver to various parts of the body, including adipose.
2. Chylomicrons deliver TG from the gut to various parts of the body, including adipose.

From adipose:
3. Adipose releases FFA (free fatty acid), which gets picked up by Albium and returned to the liver. Other tissues can tap into this stream of energy, but I’m not sure the exact uptake mechanism.

I don’t haven numbers or ratios, but I my guess is VLDL are going to be doing the bulk of the work during fasting. Especially during periods of energy demands, like exercise.

Craig

Chuck W
Guest
Chuck W

Craig,

Thanks for the reply, I had trouble finding this info from other sources.

So from the perspective of the adipose cell, release of FFA is the only “way out” for fat energy?

Thanks,
-Chuck W

annie
Guest
annie

Hi Dave –
I think that I’m a hyper-reponder as well and would be in a study if possible.
I realize that you’re not a Dr but you do have lots of experience reading the #s and I would love your opinion.

I’m 55, female and have been on a keto diet for 7 months. I’ve lost 35 lbs and am within 5 lbs of my maintenance weight. My bloodwork prior to keto was all great. Last week I had my first blood work since keto and some of the #’s are now through the roof.
Cholesterol 302
TG 60
HDL 78
VLDL calc 12
NonHDL Chol 210
LDL-P 2274
LDL-C 218
VLDL size 70
HDL-P 27.9
My Lipidologist (who is on keto but has normal bloodwork) thinks I’m possibly a hyper-absorber.

I’m seriously concerned about CVD and would love to hear your thoughts

Annie
Guest
Annie

Thank you, I appreciate your response!

Jim
Guest
Jim

Just watched your presentation at Low Carb Breckenridge and thought it was great. I will be starting (again) a LCHF diet in January and will get some blood work for your “study”. I am going to lef.org to purchase the CBC panels for $35 each. I think that is the best price around for blood work. Do you know of another I should look into?
Just started following you on Twitter as well. Thanks for your work

jim
Guest
jim

Thanks for the info…and here is what Life Extension does for the $35…they do an annual sale too where you can buy a years wort of tests: http://www.lifeextension.com/Vitamins-Supplements/itemLC381822/Chemistry-Panel-Complete-Blood-Count-CBC-Blood-Test

jim
Guest
jim

Just noticed they call it this: Chemistry Panel & Complete Blood Count (CBC) .. Sorry for the confusion

Craig Daniel Doussett
Guest
Craig Daniel Doussett

Awesome

Liz
Guest
Liz

I’ve put my numbers into your calculator (total cholesterol 7, triglycerides 2.38, HDL 1.1, LDL 4.8 and the result seems to be “high risk”, which seems ominous! However, not sure what the implications are or what I can do about it. Been LCHF for 7 months. Was 198lbs, Hba1c of 68, cholesterol 5.6 (not sure of breakdown, but triglycerides around 7, despite long-term fenofibrate and simvastatin. In December (still on drugs, but low carb AND relatively low fat – due gall bladder flare) Hb1ac was 32, total cholesterol 3.7 and triglycerides 1.6. Since Xmas, have upped the fats, but still low carb (aim for about 50gms or less a day). I have stopped the fibrate and statin and the latest results (Hba1c up slightly but still “normal” at 35) are those given at the top of this post. Should I be concerned? Should I do something to improve the profile? If so, what? All help gratefully received!

Julie
Guest
Julie

Hi Dave, thank you so much for the awesome research that you are doing. I’m a 56 yr old female. I’m a runner but have not been running much the last 3 months. I’d been training for a marathon and got up to 15 miles and crashed on energy levels. I also lift weights and do yoga. I’m not lean. 5’0 124lb. I’ve been doing keto for almost 5 months. BMI 24. I’ve only lost 3 lbs. I just got my fasting bloodwork results. glucose 59, ketones 2, A1C 5.0, CBC WBC 7.7, total cholesterol 494, Trig 79. HDL 153, LDL 322, non-hdl 341. I’m not sure why I’m not loosing weight, and get out of ketosis very easily. I eat very low carb, do intermittent fasting. And have started back on marathon training. Started back up with 6 miles and struggling on energy levels. Read your article on adding more carbs in. I’ve done low carb high protein for several years prior to LCHF

Jenny
Guest
Jenny

I’m ready for part III! Maybe you can also explain glucagon’s role in fatty acids?

Alex
Guest

I just saw both posts part 1 & 2 and they’re amazingly simple! Great job Dave! Looking forward for part 3 =D

Michael Tranchina
Guest
Michael Tranchina

I love your “disruptive” research Dave…I have been looking for answers to the cholesterol puzzle for many years…You have broken the code…I am not surprised that a systems engineer would be the one to do this…

Unless I missed it, I am trying to better understand the “inputs” that affect HDL-C blood levels…I am following your energy model with the LDL- and LDL-P, but I am still not clear on the factors that affect HDL-C?

Dawn
Guest
Dawn

Sorry I am a little confused about some terminology, I hope you can help me.
Is LDL-C the Cholesterol or is it LDL in my blood work?
I wish I could include a graphic with my question. But I will try to explain why I am asking. In your cartoon picture on this site you show “everyone boarding a blue circle” that is being called Low Density Lipoprotein” also know as LDL and the passengers are Triglycerides, Cholesterol and Fat soluble vitamins.
Then in this presentation at https://www.youtube.com/watch?v=jZu52duIqno&t=2178s&list=WL&index=16 at min 12:33 you ask “What is the cholesterol in this?(the boat)” and you then label the life-rafts LDL-C.
I am really trying make some sense out of this because i think it could be very helpful I have been low carb since before it was popular (like 20 years now) and my lipid numbers aren’t great but they do fluctuate. I am so interested in this!!!
Last test for me 3/1/17 chol 292, LDL 222, HDL 56, Tri 70. now learning I probably didn’t fast long enough (not a full 12 hours) and wonder now how much being a coffee drinker mattered too.

Dtree
Guest
Dtree

Hi Dave.

First of all- this is an amazing resource that you created- thank you so much. It really is the best explanation of the science that I’ve ever seen on this topic.

Question: Male, 35, 6’1, 185 lbs with 14% body fat per recent dexa. Life long athlete and weight stable for 10 years +. Currently 4-5 cardio sessions per week plus 3-4 weight training sessions. Started keto 12 weeks ago for general health and some GI issues.

Baseline lipids: Total: 164; HDL 63, LDL 88, Trigs-64;
After 12 weeks of keto: Total-235; HDL 64, LDL 161, Trigs 52;

If I understand correctly this is somewhat expected on keto, especially if someone is a hyper-responder. I’m not sure, however, what criteria classifies me as such (besides the 3 you list). I.e. how do I know that this rise in LDL is just due to a higher transport needs for Trigs (for energy) vs. genetic pre-disposition?

What test would you recommend to do in order to properly assess if I’m at a higher risk of CV issues, and what would you be looking for on that test? Or is the fact that my trigs went down a good enough indication that I’m ok?

Again, thanks so much for this blog. Currently devouring every article on it and sending links to friends and family.

Dtree

Siobhan Huggins
Admin

Hi there, I’m handling comments while Dave is on a hiatus for a few weeks for his anniversary.
First off – glad you’re enjoying the site and that it has been helpful for you!
Based on your lower bodyfat percentage, and switch over to a fat based diet I’m not especially surprised by your lipid profile change – it fits pretty well with others in a similar situation that I’ve seen, and with Dave’s demonstration of how the system may be working. You’ll also notice that if you run your previous and current numbers through the report tool that your remnant cholesterol has gone from 13 to 10, so both in the lowest risk category but of different degrees. More on remnant cholesterol here.

As for checking for a genetic predisposition, one thing you could do to help figure that out, is just to change the energy input. In other words, you could try to do the Feldman Protocol, and see if you get a drop. If you do, it’s likely that your numbers are simply a reflection of how you’re getting energy to your cells. Not a guarantee, but would help to suss out which it is.
Just be sure to avoid common confounders like coconut and MCT oil, heavy coffee drinking or coffee drinking on the morning of the test, and make sure to fast 12-14 hours before each test.

Dtree
Guest
Dtree

Hi Siobhan.

Thanks so much for the response- makes a lot of sense. I will definitely plan on implementing the Feldman protocol to test that hypothesis in the next 2 weeks. I’ll post here with the results.

In terms of additional tests: Is it advisable to have an NMR done? Or will the confirmation via Feldman protocol be a sufficient indication (along with very low CRP-.3) that CV risks are likely low? Any other test you’d recommend looking at?

Thanks so much for taking the time!
Dtree

Siobhan Huggins
Admin

Awesome! We do appreciate people sharing their results 🙂

As for the NMR, personally I’m in the camp of “more information is better so long as it doesn’t overly confuse things”. The most reliable risk marker I’ve seen for CVD is available from the standard lipid panel (remnant cholesterol) but I also don’t like relying on one marker alone. An NMR, and fasting insulin would help provide a little more information on risk, if you’re worried about it (if you’re curious about why, check out Ivor Cummins work).

Dtree
Guest
Dtree

Perfect, thanks so much!
Last question- I promise:
I understand the mechanism of lowering LDL by switching to carbs (Feldman protocol). But what is the mechanism for lowering the LDL by increasing the calories with high fat? Wouldn’t additional fat increase the LDL available to transport TGs?
Thanks!

Siobhan Huggins
Admin

This is because the body balances two sources of fat energy – dietary fat you just ate (transported by chylomicrons), and fat from storage (transported by VLDL, which turn into LDL once they drop off the triglycerides). As access to dietary fat goes up, need for stored fat to be transported goes down.
Chylomicrons are cleared from the system by the 12 hour mark, and when you get bloodwork done you are (or we recommend you are) 12-14 hours fasted. At that point you’re measuring the VLDL (Remnant cholesterol) and LDL.
If you increase the amount of dietary fat you take in, you decrease the need to use fat from storage, and LDL goes down as a result. The nitty gritty is explained in an article I wrote here.

Dtree
Guest
Dtree

Brilliant article!! Thank you!

Shantanu
Guest
Shantanu

This is simply brilliant! Thanks for demystifying cholesterol and more important, removing the scary halo around it.

I am now in month 14 on keto. I just got back blood results and they were consistent with this blog post. I started in Mar 2017 with an HDL 35 mg/dl, LDL 152 mg/dl and TG 62 mg/dl. Last week’s (Apr 2018) results: HDL 64, LDL 136 and TG 44. This my highest HDL and lowest TG in the 10 years for which I have records. Remnant cholesterol has gone down from 12 to 8.8.

Also, I’ve lost 60 lbs and feel the best I have in years.

Siobhan Huggins
Admin

Glad to hear the site has been helping you on your health journey, Shantanu!
Congrats on the weight loss, and health gains!

Dr. David J
Guest
Dr. David J

Too many cartoons – part #1 was def better & easier to make sense of

Siobhan Huggins
Admin

Thanks for the feedback Dr. David! This is meant to be a “Simple Guide” so if there’s any part in particular that was confusing or needs expanding on or clarification please do comment with that, it would be appreciated 🙂

Dr. David J
Guest
Dr. David J

This initial thought was from someone who has read & studied a lot over the last year about all aspects of low carb lifestyle, ketosis, diabetes & metabolic syndrome + obesity, just so you know. My thought was simply that if someone like me is having some difficulty following everything you say, a lot if not most of your other readers must also have difficulty. I’ve read almost all the books written on these topics from Jason Fung’s 3, Phinney & Volek, Nina Teicholz, Dr. Perlmutter, Jimmy Moore, Dr. Bruce Fife, Dr. Mercola, Wilson & Lowery . . . I’ve got them all & they are all saying the same thing. So, thank you for confirming the science for me & making some of it easier to understand. I just think it was a lot easier to follow with only some cartoons. Great work though & from the look of it, no doubt a lot of work!
PS: The size of the print in those cartoons is so small, it’s hard to read which of course affects the reader’s willingness to keep going.

Siobhan Huggins
Admin

That’s a completely legitimate thought for sure! Feedback is highly appreciated, especially from someone who has already done their research into the nutrition science environment as a whole. Thank you! 🙂

Sherrie
Guest
Sherrie

How can you lower you remnant cholesterol? The calculator has me at medium risk – 25 remnant cholesterol. And 0.47 CHOL to HDL. – I’ve been doing LCHF for about 4 months having my #’s go up. Was at total cholesterol 258, LDL 177, Trig. 62 and HDL 69. Now Total 281, LDL 203, Trig 125 and HDL 53. Doctor wants to put me on a statin but I’m resisting. I just want to make sure I’m making the right choice but it’s all overwhelming and hard to find doctors that support Keto.

Naren
Guest
Naren

Hi Dave.

great article very easy to understand for a non medical person

I just wanted to tell you my case
i am currently on keto since 2 months and i have blood test done, please check below and let me know if i need to take any precautionary measures

in mg/dl

HDL 35
LDL 279
VLDL 19
Total Cholestrol 334
Triglycerides 96

Elizabeth
Guest
Elizabeth

I got to say I love the low carb Community. You’ll understand why when you see my results and my question.
Before keto tc 204, hdl 51, ldl 120, tg 168
After 2 years keto tc 197 hdl 62 ldl 119 tg 76
After 5 mo. carnivore tc 182 hdl 56 ldl 113 tg76
Here are the other numbers ( no base line sorry)
Vldl 28 total LDL particles 903 rlp 121 small dense LDL lll 243 sn D’s LDL lv 70 total hdl particles 6994 large buoyant hdl 2388 Apo B100 82 Apo A1 157 Lp(a) 6.4 Metabolism syndrome traits 0 CRp 3.68 fasting insulin 9.4 homo cysteine 16.1 farthing glucose 90. my lovely zero carb Health Group pointed out that there may be a possibility of MTHFR variant and I just heard from one of my brother’s that he has been tested and found that he yes indeed has that very thing. I will be 62 next month and I have eaten a standard diet interspersed with periods of Adkins on and off for 40 years, I have been 60 to 70 lb overweight my entire adult life, and lost about 50 on keto. I have gained back 5 lb on Carnivore however I expected to because sarcopenia.. my question to you is do these look like decent numbers? I take 112 mcg. Thyroid daily and my thyroid numbers are . 61 TSH 11.7 t4 and 72 t3
Thank you

Dr. Maria Lima
Guest

Hi Dave!
Awesome job! I wisk we have it also in Spanish!
Maybe is it possible to yranslate it? Co working with Diet Doctor?
It would be great enlightening for Spanish Spoken people. We are so hungry of learning and have right info!

Robert Monahan
Guest
Robert Monahan

I know I am insulin resistant and have metabolic syndrome as a result of adipocyte and other physiological changes induced by radiation therapy as a child..I am very lean and take testosterone replacement plus synthroid. If triglycerides are very high after fasting (still above 500 after 12-16 hour fast, no coffee or tea), is this a VLDL issue? Doctor is recommending statins even though the LDL is 74 and LDL-P is ~1000? HDL is low of course..~30. The only way I have been able to get triglycerides down below 500 and HDL up above 40 is via low fat diet. LCHF improved the LDL-P with no improvement to Trigs. Is there a way for me to do high fat and to keep trigs down if there is a VLDL / insulin resistance issue?

MELYNDA SWOYER
Guest
MELYNDA SWOYER

I have struggled with hyperlipidemia. I am a nurse practitioner so of course the plan of care has always been “use a statin”. I don’t tolerate them. I have tried using lowest dose 2-3 times a week etc. While it lowered my cholesterol and LDL I noticed my triglycerides always went up! I couldn’t make sense of it. This spring I was off meds while on vacation – had steak 3 times in a week. Labs done – Total cholesterol was 300 with LDL of 200, trigs were 100. I immediately decided no beef and tried to eat very little chicken etc. Mostly plant proteins – which are high in carbs. But it’s scary to see those numbers so made an effort to implement traditional methods. By the way I am very active – I typically bicycle gravel around 30 miles a week, sometimes more, walk every day at least 3-4 miles. In July – after 6 weeks of Zetia – cholesterol lowered to 230, LDL to 130, trigs 200. But I couldn’t lose weight, felt like crap. Went off meds. Added back chicken, beef maybe once a week, lowered my carb intake – felt much better. And I immediately lost 5#. Anyway – watched your video with Zdogg. Everything made sense. Looking forward to new changes – increasing fat , lowering carbs even more.

Bryan
Guest
Bryan

Excellent description. Thank you!

Liz
Guest
Liz

Thank you so much Dave for all this amazing information. My LDL and total cholesterol jumped up after being on a low carb diet for 8 months. I’m not lean – still have quite a bit of weight to drop – so I don’t fall into your lean hyper responder category. But I’m hoping as I read more of your site I will figure out whats going on for me.

Thanks again – it’s wonderful of you to do all this research and share it with the rest of us (saving me from completely panicking about my numbers!!)